Antibiotic Discoveries and a Century of Creating Superbugs
In the pre-antibiotic era, the infections we currently see as relatively minor were sometimes deadly. This book discusses the rise (and sometimes fall) of “wonder drugs” designed to combat infections for which, at the time, there was no cure. However, history has shown us that, when antibiotics are overused, it can ultimately lead to either widespread discontinuation of the antibiotic or a drastic decrease in efficacy, leaving healthcare providers with few or no options for treatment. This book explores the discoveries of the major antibiotic drug classes, and highlights major bacterial strains which have become resistant and now represent difficult-to-treat infections. Barriers to new antibiotic development, as well as novel strategies for treating bacterial infections, are also explored.
Doreen E. Szollosi received her PhD in Pathobiology from Brown University, Rhode Island, USA, where she studied immunosuppression and lymphocyte apoptosis in a mouse model of polymicrobial sepsis. She is the Assistant Dean for Pharmacy Academic Affairs and a founding faculty member of the pharmacy program of the University of Saint Joseph, Connecticut, USA. She is passionate about working with her pharmacy practice colleagues to produce new pharmacists who will be diligent in antimicrobial stewardship in practice.
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