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Professor Jean-Luc Wautier

Hematology

University of Paris



Jean-Luc Wautier has been the Professor of Hematology at the University of Paris, France, since 1986 and is the Director of the Laboratory of Cellular Biology and the Biological Center at the same institute.

He is the author of over 300 research articles published in English and French in the most prestigious and specialized journals, including the New England Journal of Medicine, Lancet, Proceedings of the National Academy of Sciences (USA), Journal of Clinical Investigations, Blood, the British Journal of Hematology, Thrombosis & Heamostasis, the Journal of Immunology, Diabetes, Diabetologia, Circulation Research, the Journal of Biological Chemistry and Kidney International.

He has given over 350 presentations about his research at national and international meetings, and received numerous awards for his research, most recently the Mémain-Pelletier Prize in 2007; the most prestigious prize from the French National Academy of Sciences.

In his research career, spanning almost three decades, he has focused on the problem of how diabetes is a life-threatening condition. His research has led to understanding why having too high blood sugar levels in people with diabetes can cause hardening of arteries and blood vessels which leads to blindness, kidney failure and heart disease.

In particular, his research has focused on the formation of Advanced Glycation End-products (AGEs) which form from the high sugar levels present in diabetes, and how these contribute to these devastating vascular complications through interaction with a receptor on cells in the vasculature.