Hereditary and Familial Colorectal Cancer

Hereditary and Familial Colorectal Cancer

This book describes the historical context of colorectal cancer predisposition syndromes and the latest knowledge relating to each of the known hereditary colorectal cancer predisposition syndromes. There is a particular focus on the management of each of these syndromes in turn, including medical and surgical management, cancer surveillance, and screening recommendations. It also explores the workings of specialised hereditary and familial cancer clinics from the perspectives of the various clinicians involved in the running of the service. Multidisciplinary management, universal tumour screening, risk estimation, the obtaining and use of genetic information, and appropriate high-risk population screening and surveillance are also discussed, as are future developments and how these may relate to this exciting and evolving field.


Professor Desmond Winter is a consultant colorectal surgeon at St. Vincent’s University Hospital, Dublin, and Clinical Professor at the University College Dublin and the School of Medicine and Medical Sciences of the National University of Ireland in Dublin. He completed research in Ireland and at Yale University for a Doctorate of Medicine before completing his surgical training. He received the Association of Surgeons of Great Britain and Ireland Medal for the Intercollegiate Fellowship, and is the recipient of over 30 national and international scholarships and research awards. He is the author of over 300 peer-reviewed publications and a founding member of the FORESIGHT (Formally Overseeing Risk Evaluation and Surveillance of Intestinal and Gastric Hereditary Tumours) Clinic.

Dr Éanna Ryan is a specialist registrar on the Royal College of Surgeons in Ireland (RCSI) General Surgery Specialty Training programme. His post-graduate doctoral research was conducted in a multidisciplinary translational environment under the mentorship of Professor Winter at St. Vincent’s University Hospital, Dublin, and was focused on the microsatellite, immune molecular subtype of colorectal cancer. His interests include all aspects of gastrointestinal disease but particularly surgical oncology, cancer genomics, and minimally invasive surgery. He is a committee member of the Irish Surgical Trainee Group, the Irish Surgical Research Collaborative, and the European Society for Trauma and Emergency Surgery Cohort Study Dissemination Committee.

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ISBN: 1-5275-8734-7

ISBN13: 978-1-5275-8734-2

Release Date: 11th October 2022

Pages: 520

Price: £79.99