Pseudomonas aeruginosa, the Superbug

Pseudomonas aeruginosa, the Superbug

Pseudomonas aeruginosa is one of the most commonly isolated bacterial species in clinical microbiology laboratories and it causes infections in hospitalized patients with strains resistant to many antimicrobials. In addition, it can form a biofilm especially in cystic fibrosis patients and patients with medical devices. Extracellular polymeric substances (EPS) or extracellular matrixes in biofilm prevent access of antimicrobial agents, disinfectants, and host-produced immune responses. Antimicrobial resistance in Pseudomonas aeruginosa is multifactorial and can be due to mutation, transfer of genes by plasmids, or transposons, among other causes. Production of β-lactamases causes resistance to β-lactam drugs including Carbapenems.

Against this background of emergence of antibiotic resistance, this book studies different types of β-lactamases routinely produced by Pseudomonas aeruginosa strains in clinical microbiology laboratories. It shows that, although molecular methods like Polymerase Chain Reaction (PCR) are the gold standard for detection of different types of β-lactamases, they are very costly and require expertise.

Dr Silpi Basak, a prolific researcher and author in the field of Medical Microbiology, received her MBBS from University of Calcutta and her MD from Nagpur University, India. She authored 76 publications, including a number of journal articles and eight book chapters. She was a Professor in the Department of Microbiology in Jawaharlal Nehru Medical College, India. She was also a Life Member of several medical associations, including the Indian Association of Medical Microbiologists, the Indian Association of Tropical Parasitology, the Indian Medial Association, the Indian Association of Mycoplasmologists, and the Indian Association of Sports Medicine. Her research focused on the fields of antimicrobial resistance, hospital infection control, and fungal pathogens.

Dr Sanchari Das received her MBBS from Agartala Government Medical College at Tripura University of Health Sciences, India, and her MD from Jawaharlal Nehru Medical College, India. She is the author of seven journal articles, and her research focuses on Pseudomonas aeruginosa, antimicrobial resistance, and biofilm production.

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ISBN: 1-5275-8413-5

ISBN13: 978-1-5275-8413-6

Release Date: 14th July 2022

Pages: 130

Price: £66.99